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Robert W. Proctor PhD, "Attention: Selection and Control in Human Information Processing"
English | ISBN: 1433833867 | 2023 | 494 pages | PDF | 6 MB
This text presents a comprehensive and accessible overview of the science of attention, conveying its central findings and applications to real-world issues, including its relationship with technology, learning, and memory.
The study of attention is a core area of psychology that is particularly relevant today, given the ever-increasing demands on our mental workload. This book conveys the essential issues in attention research, showing how theory and research co-evolve. The authors use an interdisciplinary information-processing framework that draws from cognitive psychology and neuroscience.
Each chapter reviews a specific type of attention and related cognitive processes, including auditory and visual selective attention, attentional control and inhibition, divided attention and multitasking, sensory and working memory, and memory consolidation and information retrieval. Feature boxes help readers translate key research findings into real-world applications.
A special focus is the relationship between attention and modern technology, for example in processing multisensory input in virtual and online environments, and in situations such as air traffic control, piloting, and driving, where situation awareness is crucial. Various pathologies that affect attention are also reviewed, including ADHD, autism-spectrum disorders, dementia, and head injuries.
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Autodesk Fusion 360 PCB Black Book (V 2.0.15509) by Gaurav Verma, Matt Weber
English | March 31, 2023 | ISBN: 1774590999 | 220 pages | EPUB | 30 Mb
The Autodesk Fusion 360 PCB Black Book (V 2.0.15509) is 1st edition of our series on Autodesk Fusion 360 PCB. The book is updated on Autodesk Fusion 360 Ultimate, Student V 2.0.15509. With lots of features and thorough review, we present a book to help professionals as well as beginners in creating some of the most complex electronic design while following systematic workflow. The book follows a step-by-step methodology. In this book, we have tried to include related technical information for each PCB designing tool. We have tried to reduce the gap between educational use and industrial use of Autodesk Fusion 360 PCB. This edition of book, includes latest topics on Schematic design, 2D PCB design, 3D PCB design, PCB manufacturing, and electronic library management. The book covers almost all the information required by a learner to master Autodesk Fusion 360 PCB. Some of the salient features of this book are:
In-Depth explanation of concepts
Every new topic of this book starts with the explanation of the basic concepts. In this way, the user becomes capable of relating the things with real world.
Topics Covered
Every chapter starts with a list of topics being covered in that chapter. In this way, the user can easily find the topic of his/her interest easily.
Instruction through illustration
The instructions to perform any action are provided by maximum number of illustrations so that the user can perform the actions discussed in the book easily and effectively. There are about 340 small and large illustrations that make the learning process effective.
Tutorial point of view
At the end of concept's explanation, the tutorial makes the understanding of user firm and long lasting. Almost each chapter of the book has tutorials that are real world projects. Moreover, most of the tools in this book are discussed in the form of tutorials.
For Faculty
If you are a faculty member, then you can ask for video tutorials on any of the topic, exercise, tutorial, or concept. As faculty, you can register on our website to get electronic desk copies of our latest books, self-assessment, and solution of practical. Faculty resources are available in the Faculty Member page of our website once you login. Note that faculty registration approval is manual and it may take two days for approval before you can access the faculty website.
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Battleship Ramillies: The Final Salvo by Ian Johnston, Mick French
English | June 15, 2014 | ISBN: 1848322070 | 256 pages | MOBI | 38 Mb
HMS Ramillies was the last battleship to join the Grand Fleet in 1917 and survived to fight in the Second World War. Although the ship did not make headlines, she was actively employed from start to finish, and even survived being torpedoed by a Japanese submarine. In this respect she was typical rather than extraordinary but, like any large ship, to her crew she was unique - she was certainly the only ship in British naval history whose captain wore a grass skirt into battle (honoring a Maori belief that the ship would come to no harm while he did so; Ramillies survived the war).
This book, produced with the full cooperation of the HMS Ramillies Association, is a tribute to the ship in words and photographs, deftly assembled from a combination of interviews with surviving crew members, and carefully researched diaries and written accounts by those connected with the ship, including HRH the Duke of Edinburgh for whom Ramillies was his first ship. Many personal photo albums were unearthed to provide previously unpublished illustrations, which add a further dimension to a vivid picture of naval life in an almost-forgotten era.
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Deborah Roth Ledley, "Becoming a Calm Mom: How to Manage Stress and Enjoy the First Year of Motherhood"
English | ISBN: 1433804042 | 2008 | 265 pages | PDF | 10 MB
Having a new baby is a life-changing event that brings both delight and doubt in its wake. All new moms have thoughts such as
-Why can't I soothe my baby?
-Are other new moms handling motherhood better than I am?
-Is it selfish to want time for myself now that I have a baby who needs me?
-Will my partner and I ever stop squabbling now that baby makes three?
These kinds of thoughts can lead even the most confident women to feel stressed out and anxious.
Becoming a Calm Mom balances scientifically sound techniques from an experienced cognitive-behavioral therapist with friendly advice from fellow new moms to help moms successfully overcome the self-doubt that so often arrives along with their first bundle of joy.
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Ph.D. Kleespies, Phillip M., "Behavioral Emergencies: An Evidence-Based Resource for Evaluating and Managing Risk of Suicide, Violence, and Victimizat"
English | ISBN: 1433804069 | 2008 | 503 pages | PDF | 31 MB
In virtually every mental health clinician's career, a situation arises that requires immediate response: A client or patient presents who is suicidal, potentially violent, and/or at risk of being victimized. In such a situation-considered a behavioral emergency-the clinician may have little or no time to consult resources before responding. In this book, Phillip M. Kleespies and his colleagues provide clinicians with critical, evidence-based approaches for the evaluation and management of behavioral emergencies.
This book makes clear the distinction between a behavioral crisis, which is a serious disruption of functioning that does not necessarily imply danger, and a behavioral emergency. Guidance on behavioral emergencies is drawn from both clinical experience and empirical evidence, and the book's structure functions as a curriculum for educating both new and seasoned clinicians. Unique to this book are chapters on violence and suicide risk among adolescents, as well as individuals who are chronically ill. Contributors also discuss the legal and psychological risks associated with treating behavioral emergencies.
Comprehensive in scope, this book provides a solid knowledge base that will be an invaluable resource for all clinicians.
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Kurt Salzinger, "Behavioral Mechanisms and Psychopathology: Advancing the Explanation of Its Nature, Cause, and Treatment"
English | ISBN: 1433804522 | 2009 | 264 pages | PDF | 17 MB
This is the first book to present the leading contemporary theories and research regarding the behavioral processes that underlie major mental illnesses, including schizophrenia, bipolar disorder, anxiety disorders, eating disorders, and alcohol/drug disorders.
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Gary R Brooks Ph.D., "Beyond the Crisis of Masculinity: A Transtheoretical Model for Male-Friendly Therapy"
English | ISBN: 1433807165 | 2009 | 232 pages | PDF | 15 MB
Explores the 'psychopathology of men's everyday lives' - the maladaptive strategies that men use to maintain a traditional male role that has increasingly come under assault. This title investigates the related question of why men overwhelmingly reject psychotherapy at a time when they need it the most.
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Toshikazu S. Foley, "Biblical Translation in Chinese and Greek: Verbal Aspect in Theory and Practice"
English | 2009 | pages: 477 | ISBN: 9004178651 | PDF | 13,8 mb
This study integrates three independent subjects - translation theory, Mandarin aspect, and Greek aspect - for the purpose of formulating a working theory applicable to translating the Bible. The primary objectives are defined in terms of grammatical translation of Greek aspect into Mandarin aspect at the discourse level. A historical overview of the Chinese Bible is provided as a way of introducing major translation issues related to linguistic, conceptual, and logistical challenges. The proposed theory provides the translator with a powerful tool, which is tested in two sample passages from John 18-19 and 1 Corinthians 15. Provided, also, are critical reviews of over sixty Chinese Bible versions, Nestorian, Manichaean, Catholic documents, and a translation written according to the proposed theory.
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Eugene E. García, "Bilingualism and Cognition: Informing Research, Pedagogy, and Policy"
English | ISBN: 143380879X | 2011 | 242 pages | PDF | 3 MB
Bridging the fields of cognitive psychology and education, this volume presents research-based knowledge on language acquisition and learning to leverage the strengths and achievements of bilingual children. By understanding the neurocognitive mechanisms of the bilingual brain and the need for socioculturally inclusive pedagogy, educational researchers and practitioners can better serve this rapidly growing population.
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Bioceramics: Materials and Applications V, Volume 164 By
2006 | 128 Pages | ISBN: 1574981854 | PDF | 8 MB
This proceedings includes papers on ceramics and glasses used in biomedical, dental and biological applications, including biomimetics and natural bioceramic materials. Topics include: materials; applications; biomimetic materials and synthesis; structure/properties of natural ceramic-based materials; behavior in biological environments; and synthesis, processing, characterization, and properties.Content:
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Biodiversity: Exploring Values and Priorities in Conservation By Dan L. Perlman, Glenn Adelson(auth.)
1997 | 197 Pages | ISBN: 086542439X | PDF | 15 MB
Biodiversity has become a buzzword in the environmental movement and in science, and is increasingly being taught in university degree courses. This new text is designed as a primer, giving non-specialists an introduction to the historical context, current debates, and ongoing research in this subject. Content: Chapter 1 Legacies (pages 1-17): Chapter 2 Conceptual Problems with Biodiversity (pages 18-36): Chapter 3 The Role of Values (pages 37-51): Chapter 4 Diversity (pages 52-66): Chapter 5 Mapping the Patterns of Biodiversity (pages 67-101): Chapter 6 Ambiguities (pages 102-124): Chapter 7 Inventories (pages 125-138): Chapter 8 Articulating Goals and Setting Priorities (pages 139-154): Chapter 9 Future Directions (pages 155-169):
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Bioequivalence Studies in Drug Development: Methods and Applications By Dieter Hauschke, Volker Steinijans, Iris Pigeot(auth.)
2007 | 321 Pages | ISBN: 0470094753 | PDF | 7 MB
Studies in bioequivalence are the commonly accepted method to demonstrate therapeutic equivalence between two medicinal products. Savings in time and cost are substantial when using bioequivalence as an established surrogate marker of therapeutic equivalence. For this reason the design, performance and evaluation of bioequivalence studies have received major attention from academia, the pharmaceutical industry and health authorities. Bioequivalence Studies in Drug Development focuses on the planning, conducting, analysing and reporting of bioequivalence studies, covering all aspects required by regulatory authorities. This text presents the required statistical methods, and with an outstanding practical emphasis, demonstrates their applications through numerous examples using real data from drug development. Includes all the necessary pharmacokinetic background information. Presents parametric and nonparametric statistical techniques. Describes adequate methods for power and sample size determination. Includes appropriate presentation of results from bioequivalence studies. Provides a practical overview of the design and analysis of bioequivalence studies. Presents the recent developments in methodology, including population and individual bioequivalence. Reviews the regulatory guidelines for such studies, and the existing global discrepancies. Discusses the designs and analyses of drug-drug and food-drug interaction studies. Bioequivalence Studies in Drug Development is written in an accessible style that makes it ideal for pharmaceutical scientists, clinical pharmacologists, and medical practitioners, as well as biometricians working in the pharmaceutical industry. It will also be of great value for professionals from regulatory bodies assessing bioequivalence studies.Content: Chapter 1 Introduction (pages 1-16): Chapter 2 Metrics to Characterize Concentration?Time Profiles in Single? and Multiple?Dose Bioequivalence Studies (pages 17-36): Chapter 3 Basic Statistical Considerations (pages 37-68): Chapter 4 Assessment of Average Bioequivalence in the RT/TR design (pages 69-104): Chapter 5 Power and Sample Size Determination for Testing Average Bioequivalence in the RT/TR Design (pages 105-122): Chapter 6 Presentation of Bioequivalence Studies (pages 123-155): Chapter 7 Designs with more than Two Formulations (pages 157-173): Chapter 8 Analysis of Pharmacokinetic Interactions (pages 175-203): Chapter 9 Population and Individual Bioequivalence (pages 205-282): Chapter 10 Equivalence Assessment for Clinical Endpoints (pages 283-306):
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Bioethics for beginners: 60 Cases and Cautions from the Moral Frontier of Healthcare By Glenn McGee(auth.)
2012 | 181 Pages | ISBN: 0470659114 | PDF | 1 MB
How far is too far? 60 cases illustrating modern bioethical dilemmasBioethics for Beginners maps the giant dilemmas posed by new technologies and medical choices, using 60 cases taken from our headlines, and from the worlds of medicine and science. This eminently readable book takes it one case at a time, shedding light on the social, economic and legal side of 21st century medicine while giving the reader an informed basis on which to answer personal, practical questions. Unlocking the debate behind the headlines, this book combines clear thinking with the very latest in science and medicine, enabling readers to decide for themselves exactly what the scientific future should hold. Content: Chapter One Tip?Toe when Walking on the Bleeding Edge (pages 1-16): Chapter Two Everybody Lies (pages 17-33): Chapter Three The Genome Isn't What It Used to Be (pages 34-39): Chapter Four Reproduce at Your Own Peril (pages 40-56): Chapter Five Don't Sweat the Nano?Sized Stuff (pages 57-68): Chapter Six The State Will Protect Your Health Right Up Until It Doesn't (pages 69-85): Chapter Seven "Do No Harm" Has Become "Care for Yourself" (pages 86-97): Chapter Eight You Aren't Dead Until Someone Tells You So (pages 98-109): Chapter Nine Eat Only Food for Thought (pages 110-116): Chapter Ten Beware of Ideologues and Demagogues (pages 117-145):
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Biological Reaction Engineering: Dynamic Modelling Fundamentals with Simulation Examples, Second Edition By Dr. Irving J. Dunn, Professor Dr. Elmar Heinzle, Dr. John Ingham, Dr. Jiri E. Prenosil(auth.)
2003 | 521 Pages | ISBN: 3527307591 | PDF | 28 MB
In this book, the modelling of dynamic biological engineering processes is presented in a highly understandable way using the unique combination of simplified fundamental theory and direct hands-on computer simulation. The mathematics is kept to a minimum, and yet the 60 examples supplied on a CD-ROM illustrate almost every aspect of biological engineering science. Each example is described in detail, including the model equations. The programms are written in the modern user-friendly simulation language Berkeley Madonna, which can be run on both Windows PC and Power-Macintosh computers. Madonna solves models comprising many ordinary differential equations using very simple programming, including arrays. It is so powerful that the model parameters may be defined as "sliders", which allow the effect of their change on the model behavior to be seen almost immediately. Data may be included for curve fitting, and sensitivity or multiple runs may be performed. The results can be seen simultaneously on multiple-graph windows or by using overlays. The examples can be varied to fit any real situation, and the suggested exercises provide practical guidance. The extensive experience of the authors, both in university teaching and international courses, is reflected in this well-balanced presentation, which is suitable for the teacher, the student, the biochemist or the engineer. Content: Chapter 1 Modelling Principles (pages 9-53): Chapter 2 Basic Bioreactor Concepts (pages 55-66): Chapter 3 Biological Kinetics (pages 67-100): Chapter 4 Bioreactor Modelling (pages 101-116): Chapter 5 Mass Transfer (pages 117-143): Chapter 6 Diffusion and Biological Reaction In Immobilized Biocatalyst Systems (pages 145-160): Chapter 7 Automatic Bioprocess Control Fundamentals (pages 161-179): Chapter 8 Simulation Examples of Biological Reaction Processes Using Berkeley Madonna: Sections 8.1 ? 8.2 (pages 192-224): Chapter 8 Simulation Examples of Biological Reaction Processes Using Berkeley Madonna: Section 8.3 (pages 224-257): Chapter 8 Simulation Examples of Biological Reaction Processes Using Berkeley Madonna: Sections 8.4.1 ? 8.4.7 (pages 257-289): Chapter 8 Simulation Examples of Biological Reaction Processes Using Berkeley Madonna: Sections 8.4.8 ? 8.4.13 (pages 290-317): Chapter 8 Simulation Examples of Biological Reaction Processes Using Berkeley Madonna: Section 8.5 (pages 318-353): Chapter 8 Simulation Examples of Biological Reaction Processes Using Berkeley Madonna: Section 8.6 (pages 354-371): Chapter 8 Simulation Examples of Biological Reaction Processes Using Berkeley Madonna: Section 8.7 (pages 371-399): Chapter 8 Simulation Examples of Biological Reaction Processes Using Berkeley Madonna: Sections 8.8.1 ? 8.8.5 (pages 400-425): Chapter 8 Simulation Examples of Biological Reaction Processes Using Berkeley Madonna: Sections 8.8.6 ? 8.8.9 (pages 425-450): Chapter 8 Simulation Examples of Biological Reaction Processes Using Berkeley Madonna: Section 8.9 (pages 451-482):
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Biology of Sensory Systems, Second Edition By C. U. M. Smith(auth.)
2009 | 514 Pages | ISBN: 0470518626 | PDF | 37 MB
Since publication of the first edition, huge developments have taken place in sensory biology research and new insights have been provided in particular by molecular biology. These show the similarities in the molecular architecture and in the physiology of sensory cells across species and across sensory modality and often indicate a common ancestry dating back over half a billion years. Biology of Sensory Systemshas thus been completely revised and takes a molecular, evolutionary and comparative approach, providing an overview of sensory systems in vertebrates, invertebrates and prokaryotes, with a strong focus on human senses. Written by a renowned author with extensive teaching experience, the book covers, in six parts, the general features of sensory systems, the mechanosenses, the chemosenses, the senses which detect electromagnetic radiation, other sensory systems including pain, thermosensitivity and some of the minority senses and, finally, provides an outline and discussion of philosophical implications. New in this edition:Greater emphasis on molecular biology and intracellular mechanisms New chapter on genomics and sensory systems Sections on TRP channels, synaptic transmission, evolution of nervous systems, arachnid mechanosensitive sensilla and photoreceptors, electroreception in the Monotremata, language and the FOXP2 gene, mirror neurons and the molecular biology of pain Updated passages on human olfaction and gustation. Over four hundred illustrations, boxes containing supplementary material and self-assessment questions and a full bibliography at the end of each part make Biology of Sensory Systems essential reading for undergraduate students of biology, zoology, animal physiology, neuroscience, anatomy and physiological psychology. The book is also suitable for postgraduate students in more specialised courses such as vision sciences, optometry, neurophysiology, neuropathology, developmental biology. Praise from the reviews of the first edition:"An excellent advanced undergraduate/postgraduate textbook." ASLIB BOOK GUIDE"The emphasis on comparative biology and evolution is one of the distinguishing features of this self-contained book. .... this is an informative and thought-provoking text..." TIMES HIGHER EDUCATIONAL SUPPLEMENTContent: Chapter 1 Elements (pages 1-18): Chapter 2 Membranes, Action Potentials, Synapses (pages 19-30): Chapter 3 General Features of Sensory Systems (pages 31-39): Chapter 4 Classification and Phylogeny (pages 41-56): Chapter 5 Genes, Genomics and Neurosensory Systems (pages 57-72): Chapter 6 Mechanosensitivity of Cell Membranes (pages 75-83): Chapter 7 Kinaesthesia (pages 85-97): Chapter 8 Touch (pages 99-121): Chapter 9 Equilibrium and Hearing: The Uses of Hair Cells (pages 123-146): Chapter 10 Cerebral Analysis (pages 147-185): Chapter 11 Chemosensitivity in Prokaryocytes (pages 189-194): Chapter 12 Mammalian Chemo?Enteroreceptors (pages 195-201): Chapter 13 Gustation (pages 203-217): Chapter 14 Olfaction (pages 219-243): Chapter 15 Invertebrate Vision (pages 253-279): Chapter 16 The Human Eye (pages 281-314): Chapter 17 The Retina (pages 315-351): Chapter 18 Visual Pathways and Cortices (pages 353-378): Chapter 19 Other Vertebrate Visual Systems (pages 379-412): Chapter 20 Thermosensitivity (pages 415-421): Chapter 21 Minority Senses (pages 423-436): Chapter 22 Pain (pages 437-461): Chapter 23 Summing Up (pages 465-478): Chapter 24 Philosophical Postscript (pages 479-495):
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Biomaterials Science - Processing, Properties, and Applications, Volume 228 By
2011 | 190 Pages | ISBN: 1118060016 | PDF | 6 MB
This book contains 18 papers from the Next Generation Biomaterials and Surface Properties of Biomaterials symposia held during the 2010 Materials Science and Technology (MS&T'10) meeting, October 17-21, 2010, Houston, Texas. Topics include: Biocompatible Coatings; Drug Delivery and Anti-Microbial Coatings; Ceramic and Metallic Biomaterials; Biomaterials for Tissue Engineering; and Surface Modification.Content:
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Biomaterials Science: Processing, Properties and Applications II: Ceramic Transactions, Volume 237 By
2012 | 268 Pages | ISBN: 111827332X | PDF | 8 MB
With contributed papers from the 2011 Materials Science and Technology symposia, this is a useful one-stop resource for understanding the most important issues involved in the processing, properties, and applications of biomaterials science. Logically organized and carefully selected, the articles cover the themes of the symposia: Next Generation Biomaterials: and Surface Properties of Biomaterials. An essential reference for government labs as well as academics in mechanical and chemical engineering, materials and or ceramics, and chemistry.Content:
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Biostatistics for Oral Healthcare By Jay S. Kim, Ronald J. Dailey(auth.)
2007 | 330 Pages | ISBN: 081382818X | PDF | 5 MB
Biostatistics for Oral Healthcare offers students, practitioners and instructors alike a comprehensive guide to mastering biostatistics and their application to oral healthcare. Drawing on situations and methods from dentistry and oral healthcare, this book provides a thorough treatment of statistical concepts in order to promote in-depth and correct comprehension, supported throughout by technical discussion and a multitude of practical examples.Content: Chapter 1 Introduction (pages 1-3): Chapter 2 Summarizing Data and Clinical Trials (pages 5-25): Chapter 3 Measures of Central Tendency, Dispersion, and Skewness (pages 27-53): Chapter 4 Probability (pages 55-79): Chapter 5 Probability Distributions (pages 81-102): Chapter 6 Sampling Distributions (pages 103-111): Chapter 7 Confidence Intervals and Sample Size (pages 113-126): Chapter 8 Hypothesis Testing: One?Sample Case (pages 127-157): Chapter 9 Hypothesis Testing: Two?Sample Case (pages 159-179): Chapter 10 Categorical Data Analysis (pages 181-201): Chapter 11 Regression Analysis and Correlation (pages 203-225): Chapter 12 One?Way Analysis of Variance (pages 227-243): Chapter 13 Two?Way Analysis of Variance (pages 245-256): Chapter 14 Non?Parametric Statistics (pages 257-277): Chapter 15 Survival Analysis (pages 279-298):
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Biotechnology: A: Recombinant Proteins, Monoclonal Antibodies, and Therapeutic Genes, Volume 5a, Second Edition By
1999 | 564 Pages | ISBN: 3527283153 | PDF | 25 MB
In the field of medicinal biotechnology three major developments have caused a revolution in research that has a lot of innovative effects on clinical medicine and future applications on humans. With the availability of tailored recombinant proteins and the opportunity to produce high amounts of monoclonal antibodies new diagnostic applications have emerged and many therapeutic perspectives, e.g. in the treatment of multiple sclerosis and of cancer, are being discussed today. The aim of somatic gene therapy is to re-establish normal cell function by supplying the cells with the respective intact gene. This is a very difficult task and different diseases, e.g. AIDS and several metabolic disorders, are under investigation now. So far first promising approaches exist in cancer therapy. Moreover the book informs about regulatory and economic aspects of these new methods and their applications. Content: Chapter 1 Types and Function of Proteins (pages 1-41): Sabine Wolf and Hans Gunter GassenChapter 2 Sequence and Structure of Proteins (pages 43-86): Frank Eisenhaber and Peer BorkChapter 3 Protein Interactions (pages 87-108): Michael Meyer and Dietmar SchomburgChapter 4 In vitro Folding of Inclusion Body Proteins on an Industrial Scale (pages 110-123): Rainer Rudolph, Hauke Lilie and Elisabeth SchwarzChapter 5 Medical Applications of Recombinant Proteins in Humans and Animals (pages 125-188): Gayle Delmonte WetzelChapter 6 Enzymes for Industrial Applications (pages 189-216): Wolfgang Aehle and Onno MissetChapter 7 Antibody Engineering and Expression (pages 218-244): John R. AdairChapter 8 Manufacture of Therapeutic Antibodies (pages 245-274): Andrew J. Racher, Jerry M. Tong and Julian BonnerjeaChapter 9 Use of Antibodies for Immunopurification (pages 275-288): David J. KingChapter 10 Preclinical Testing of Antibodies: Pharmacology, Kinetics and Immunogenicity (pages 289-302): Roly Foulkes and Sue StephensChapter 11 Preclinical Testing of Antibodies: Safety Aspects (pages 303-310): Ronald W. JamesChapter 12 Therapeutic Applications of Monoclonal Antibodies: A Clinical Overview (pages 311-326): Mark SopwithChapter 13 Antibodies for Sepsis: Some Lessons Learnt (pages 328-341): Steven M. OpalChapter 14 An Engineered Human Antibody for Chronic Therapy: CDP571 (pages 343-353): Mark Sopwith and Sue StephensChapter 15 Antibody Targeted Chemotherapy (pages 355-364): Mark S. Berger, Philip R. Hamann and Mark SopwithChapter 16 ReoPro Clinical Development: A Case Study (pages 365-380): Harlan F. WeismanChapter 17 Overview of Gene Therapy (pages 382-393): Andrew MountainChapter 18 Viral Vectors for Gene Therapy (pages 395-425): Barrie J. CarterChapter 19 Non?Viral Vectors for Gene Therapy (pages 427-441): Neil WeirChapter 20 Issues of Large?Scale Plasmid DNA Manufacturing (pages 443-469): Martin SchleefChapter 21 Gene Therapy for HIV Infection (pages 471-492): Mark C. Poznansky, Myra McClure and Gregor B. AdamsChapter 22 Regulation of Antibodies and Recombinant Proteins (pages 494-516): Julie Foulkes and Gillian TraynorChapter 23 Regulation of Human Gene Therapy (pages 517-530): James ParkerChapter 24 Economic Considerations (pages 531-542): Ian J. Nicholson
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Biotechnology: Biotransformations I, Volume 8a, Second Edition By
1998 | 606 Pages | ISBN: 3527283188 | PDF | 17 MB
Biotransformations have developed into an important tool of organic synthesis. Most synthetic sequences will benefit from the use of a biotransformation step, and the use of multiple enzyme single pot reactions enables several steps to be telescoped together. Volumes 8a and b provide a comprehensive guide to the established and emerging uses of enzymes. Each chapter is devoted to a single class of transformation so that the competing possibilities can be readily compared, and there is a strong emphasis on practical and reliable reactions. Topics included in Volume 8a are: Perspectives/ Practical Aspects/ Lipases/ Esterases/ Cleavage of Amide Bonds/ Nitriles/ Alkaloids/ Yeast/ Alcohol Dehydrogenases/ Hydroxylation and Dihydroxylation/ Flavin Monooxygenases Major topics of Volume 8b: Phosphorylation/ C-C Bond Formation/ Formation of Glycoside Bonds/ Synthetic ApplicationsContent: Chapter 1 Perspectives in Biotransformations (pages 5-23): Michael K. TurnerChapter 2 Biotransformations?Practical Aspects (pages 25-34): David R. KellyChapter 3 Biotransformations with Lipases (pages 36-191): Romas J. Kazlauskas and Uwe T. BornscheuerChapter 4 Esterases (pages 193-241): Sara J. PhythianChapter 5 Cleavage and Formation of Amide Bonds (pages 243-275): David W. T. HoopleChapter 6 Nitriles (pages 277-324): Alan William BunchChapter 7 Alkaloids (pages 326-361): Neil C. BruceChapter 8 Yeast (pages 363-389): Stefano ServiChapter 9 Dehydrogenases?Characteristics, Design of Reaction Conditions, and Applications (pages 391-473): Jorg PetersChapter 10 Hydroxylation and Dihydroxylation (pages 475-533): Herbert L. HollandChapter 11 Flavin Monooxygenases-Uses as Catalysts for Baeyer?Villiger Ring Expansion and Heteroatom Oxidation (pages 535-587): David R. Kelly, Peter W. H. Wan and Jenny Tang
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