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Biological Reaction Engineering: Dynamic Modelling Fundamentals with Simulation Examples, Second Edition By Dr. Irving J. Dunn, Professor Dr. Elmar Heinzle, Dr. John Ingham, Dr. Jiri E. Prenosil(auth.)
2003 | 521 Pages | ISBN: 3527307591 | PDF | 28 MB
In this book, the modelling of dynamic biological engineering processes is presented in a highly understandable way using the unique combination of simplified fundamental theory and direct hands-on computer simulation. The mathematics is kept to a minimum, and yet the 60 examples supplied on a CD-ROM illustrate almost every aspect of biological engineering science. Each example is described in detail, including the model equations. The programms are written in the modern user-friendly simulation language Berkeley Madonna, which can be run on both Windows PC and Power-Macintosh computers. Madonna solves models comprising many ordinary differential equations using very simple programming, including arrays. It is so powerful that the model parameters may be defined as "sliders", which allow the effect of their change on the model behavior to be seen almost immediately. Data may be included for curve fitting, and sensitivity or multiple runs may be performed. The results can be seen simultaneously on multiple-graph windows or by using overlays. The examples can be varied to fit any real situation, and the suggested exercises provide practical guidance. The extensive experience of the authors, both in university teaching and international courses, is reflected in this well-balanced presentation, which is suitable for the teacher, the student, the biochemist or the engineer. Content: Chapter 1 Modelling Principles (pages 9-53): Chapter 2 Basic Bioreactor Concepts (pages 55-66): Chapter 3 Biological Kinetics (pages 67-100): Chapter 4 Bioreactor Modelling (pages 101-116): Chapter 5 Mass Transfer (pages 117-143): Chapter 6 Diffusion and Biological Reaction In Immobilized Biocatalyst Systems (pages 145-160): Chapter 7 Automatic Bioprocess Control Fundamentals (pages 161-179): Chapter 8 Simulation Examples of Biological Reaction Processes Using Berkeley Madonna: Sections 8.1 ? 8.2 (pages 192-224): Chapter 8 Simulation Examples of Biological Reaction Processes Using Berkeley Madonna: Section 8.3 (pages 224-257): Chapter 8 Simulation Examples of Biological Reaction Processes Using Berkeley Madonna: Sections 8.4.1 ? 8.4.7 (pages 257-289): Chapter 8 Simulation Examples of Biological Reaction Processes Using Berkeley Madonna: Sections 8.4.8 ? 8.4.13 (pages 290-317): Chapter 8 Simulation Examples of Biological Reaction Processes Using Berkeley Madonna: Section 8.5 (pages 318-353): Chapter 8 Simulation Examples of Biological Reaction Processes Using Berkeley Madonna: Section 8.6 (pages 354-371): Chapter 8 Simulation Examples of Biological Reaction Processes Using Berkeley Madonna: Section 8.7 (pages 371-399): Chapter 8 Simulation Examples of Biological Reaction Processes Using Berkeley Madonna: Sections 8.8.1 ? 8.8.5 (pages 400-425): Chapter 8 Simulation Examples of Biological Reaction Processes Using Berkeley Madonna: Sections 8.8.6 ? 8.8.9 (pages 425-450): Chapter 8 Simulation Examples of Biological Reaction Processes Using Berkeley Madonna: Section 8.9 (pages 451-482):

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Biology of Sensory Systems, Second Edition By C. U. M. Smith(auth.)
2009 | 514 Pages | ISBN: 0470518626 | PDF | 37 MB
Since publication of the first edition, huge developments have taken place in sensory biology research and new insights have been provided in particular by molecular biology. These show the similarities in the molecular architecture and in the physiology of sensory cells across species and across sensory modality and often indicate a common ancestry dating back over half a billion years. Biology of Sensory Systemshas thus been completely revised and takes a molecular, evolutionary and comparative approach, providing an overview of sensory systems in vertebrates, invertebrates and prokaryotes, with a strong focus on human senses. Written by a renowned author with extensive teaching experience, the book covers, in six parts, the general features of sensory systems, the mechanosenses, the chemosenses, the senses which detect electromagnetic radiation, other sensory systems including pain, thermosensitivity and some of the minority senses and, finally, provides an outline and discussion of philosophical implications. New in this edition:Greater emphasis on molecular biology and intracellular mechanisms New chapter on genomics and sensory systems Sections on TRP channels, synaptic transmission, evolution of nervous systems, arachnid mechanosensitive sensilla and photoreceptors, electroreception in the Monotremata, language and the FOXP2 gene, mirror neurons and the molecular biology of pain Updated passages on human olfaction and gustation. Over four hundred illustrations, boxes containing supplementary material and self-assessment questions and a full bibliography at the end of each part make Biology of Sensory Systems essential reading for undergraduate students of biology, zoology, animal physiology, neuroscience, anatomy and physiological psychology. The book is also suitable for postgraduate students in more specialised courses such as vision sciences, optometry, neurophysiology, neuropathology, developmental biology. Praise from the reviews of the first edition:"An excellent advanced undergraduate/postgraduate textbook." ASLIB BOOK GUIDE"The emphasis on comparative biology and evolution is one of the distinguishing features of this self-contained book. .... this is an informative and thought-provoking text..." TIMES HIGHER EDUCATIONAL SUPPLEMENTContent: Chapter 1 Elements (pages 1-18): Chapter 2 Membranes, Action Potentials, Synapses (pages 19-30): Chapter 3 General Features of Sensory Systems (pages 31-39): Chapter 4 Classification and Phylogeny (pages 41-56): Chapter 5 Genes, Genomics and Neurosensory Systems (pages 57-72): Chapter 6 Mechanosensitivity of Cell Membranes (pages 75-83): Chapter 7 Kinaesthesia (pages 85-97): Chapter 8 Touch (pages 99-121): Chapter 9 Equilibrium and Hearing: The Uses of Hair Cells (pages 123-146): Chapter 10 Cerebral Analysis (pages 147-185): Chapter 11 Chemosensitivity in Prokaryocytes (pages 189-194): Chapter 12 Mammalian Chemo?Enteroreceptors (pages 195-201): Chapter 13 Gustation (pages 203-217): Chapter 14 Olfaction (pages 219-243): Chapter 15 Invertebrate Vision (pages 253-279): Chapter 16 The Human Eye (pages 281-314): Chapter 17 The Retina (pages 315-351): Chapter 18 Visual Pathways and Cortices (pages 353-378): Chapter 19 Other Vertebrate Visual Systems (pages 379-412): Chapter 20 Thermosensitivity (pages 415-421): Chapter 21 Minority Senses (pages 423-436): Chapter 22 Pain (pages 437-461): Chapter 23 Summing Up (pages 465-478): Chapter 24 Philosophical Postscript (pages 479-495):

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Biomaterials Science - Processing, Properties, and Applications, Volume 228 By
2011 | 190 Pages | ISBN: 1118060016 | PDF | 6 MB
This book contains 18 papers from the Next Generation Biomaterials and Surface Properties of Biomaterials symposia held during the 2010 Materials Science and Technology (MS&T'10) meeting, October 17-21, 2010, Houston, Texas. Topics include: Biocompatible Coatings; Drug Delivery and Anti-Microbial Coatings; Ceramic and Metallic Biomaterials; Biomaterials for Tissue Engineering; and Surface Modification.Content:

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Biomaterials Science: Processing, Properties and Applications II: Ceramic Transactions, Volume 237 By
2012 | 268 Pages | ISBN: 111827332X | PDF | 8 MB
With contributed papers from the 2011 Materials Science and Technology symposia, this is a useful one-stop resource for understanding the most important issues involved in the processing, properties, and applications of biomaterials science. Logically organized and carefully selected, the articles cover the themes of the symposia: Next Generation Biomaterials: and Surface Properties of Biomaterials. An essential reference for government labs as well as academics in mechanical and chemical engineering, materials and or ceramics, and chemistry.Content:

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Biostatistics for Oral Healthcare By Jay S. Kim, Ronald J. Dailey(auth.)
2007 | 330 Pages | ISBN: 081382818X | PDF | 5 MB
Biostatistics for Oral Healthcare offers students, practitioners and instructors alike a comprehensive guide to mastering biostatistics and their application to oral healthcare. Drawing on situations and methods from dentistry and oral healthcare, this book provides a thorough treatment of statistical concepts in order to promote in-depth and correct comprehension, supported throughout by technical discussion and a multitude of practical examples.Content: Chapter 1 Introduction (pages 1-3): Chapter 2 Summarizing Data and Clinical Trials (pages 5-25): Chapter 3 Measures of Central Tendency, Dispersion, and Skewness (pages 27-53): Chapter 4 Probability (pages 55-79): Chapter 5 Probability Distributions (pages 81-102): Chapter 6 Sampling Distributions (pages 103-111): Chapter 7 Confidence Intervals and Sample Size (pages 113-126): Chapter 8 Hypothesis Testing: One?Sample Case (pages 127-157): Chapter 9 Hypothesis Testing: Two?Sample Case (pages 159-179): Chapter 10 Categorical Data Analysis (pages 181-201): Chapter 11 Regression Analysis and Correlation (pages 203-225): Chapter 12 One?Way Analysis of Variance (pages 227-243): Chapter 13 Two?Way Analysis of Variance (pages 245-256): Chapter 14 Non?Parametric Statistics (pages 257-277): Chapter 15 Survival Analysis (pages 279-298):

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Biotechnology: A: Recombinant Proteins, Monoclonal Antibodies, and Therapeutic Genes, Volume 5a, Second Edition By
1999 | 564 Pages | ISBN: 3527283153 | PDF | 25 MB
In the field of medicinal biotechnology three major developments have caused a revolution in research that has a lot of innovative effects on clinical medicine and future applications on humans. With the availability of tailored recombinant proteins and the opportunity to produce high amounts of monoclonal antibodies new diagnostic applications have emerged and many therapeutic perspectives, e.g. in the treatment of multiple sclerosis and of cancer, are being discussed today. The aim of somatic gene therapy is to re-establish normal cell function by supplying the cells with the respective intact gene. This is a very difficult task and different diseases, e.g. AIDS and several metabolic disorders, are under investigation now. So far first promising approaches exist in cancer therapy. Moreover the book informs about regulatory and economic aspects of these new methods and their applications. Content: Chapter 1 Types and Function of Proteins (pages 1-41): Sabine Wolf and Hans Gunter GassenChapter 2 Sequence and Structure of Proteins (pages 43-86): Frank Eisenhaber and Peer BorkChapter 3 Protein Interactions (pages 87-108): Michael Meyer and Dietmar SchomburgChapter 4 In vitro Folding of Inclusion Body Proteins on an Industrial Scale (pages 110-123): Rainer Rudolph, Hauke Lilie and Elisabeth SchwarzChapter 5 Medical Applications of Recombinant Proteins in Humans and Animals (pages 125-188): Gayle Delmonte WetzelChapter 6 Enzymes for Industrial Applications (pages 189-216): Wolfgang Aehle and Onno MissetChapter 7 Antibody Engineering and Expression (pages 218-244): John R. AdairChapter 8 Manufacture of Therapeutic Antibodies (pages 245-274): Andrew J. Racher, Jerry M. Tong and Julian BonnerjeaChapter 9 Use of Antibodies for Immunopurification (pages 275-288): David J. KingChapter 10 Preclinical Testing of Antibodies: Pharmacology, Kinetics and Immunogenicity (pages 289-302): Roly Foulkes and Sue StephensChapter 11 Preclinical Testing of Antibodies: Safety Aspects (pages 303-310): Ronald W. JamesChapter 12 Therapeutic Applications of Monoclonal Antibodies: A Clinical Overview (pages 311-326): Mark SopwithChapter 13 Antibodies for Sepsis: Some Lessons Learnt (pages 328-341): Steven M. OpalChapter 14 An Engineered Human Antibody for Chronic Therapy: CDP571 (pages 343-353): Mark Sopwith and Sue StephensChapter 15 Antibody Targeted Chemotherapy (pages 355-364): Mark S. Berger, Philip R. Hamann and Mark SopwithChapter 16 ReoPro Clinical Development: A Case Study (pages 365-380): Harlan F. WeismanChapter 17 Overview of Gene Therapy (pages 382-393): Andrew MountainChapter 18 Viral Vectors for Gene Therapy (pages 395-425): Barrie J. CarterChapter 19 Non?Viral Vectors for Gene Therapy (pages 427-441): Neil WeirChapter 20 Issues of Large?Scale Plasmid DNA Manufacturing (pages 443-469): Martin SchleefChapter 21 Gene Therapy for HIV Infection (pages 471-492): Mark C. Poznansky, Myra McClure and Gregor B. AdamsChapter 22 Regulation of Antibodies and Recombinant Proteins (pages 494-516): Julie Foulkes and Gillian TraynorChapter 23 Regulation of Human Gene Therapy (pages 517-530): James ParkerChapter 24 Economic Considerations (pages 531-542): Ian J. Nicholson

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Biotechnology: Biotransformations I, Volume 8a, Second Edition By
1998 | 606 Pages | ISBN: 3527283188 | PDF | 17 MB
Biotransformations have developed into an important tool of organic synthesis. Most synthetic sequences will benefit from the use of a biotransformation step, and the use of multiple enzyme single pot reactions enables several steps to be telescoped together. Volumes 8a and b provide a comprehensive guide to the established and emerging uses of enzymes. Each chapter is devoted to a single class of transformation so that the competing possibilities can be readily compared, and there is a strong emphasis on practical and reliable reactions. Topics included in Volume 8a are: Perspectives/ Practical Aspects/ Lipases/ Esterases/ Cleavage of Amide Bonds/ Nitriles/ Alkaloids/ Yeast/ Alcohol Dehydrogenases/ Hydroxylation and Dihydroxylation/ Flavin Monooxygenases Major topics of Volume 8b: Phosphorylation/ C-C Bond Formation/ Formation of Glycoside Bonds/ Synthetic ApplicationsContent: Chapter 1 Perspectives in Biotransformations (pages 5-23): Michael K. TurnerChapter 2 Biotransformations?Practical Aspects (pages 25-34): David R. KellyChapter 3 Biotransformations with Lipases (pages 36-191): Romas J. Kazlauskas and Uwe T. BornscheuerChapter 4 Esterases (pages 193-241): Sara J. PhythianChapter 5 Cleavage and Formation of Amide Bonds (pages 243-275): David W. T. HoopleChapter 6 Nitriles (pages 277-324): Alan William BunchChapter 7 Alkaloids (pages 326-361): Neil C. BruceChapter 8 Yeast (pages 363-389): Stefano ServiChapter 9 Dehydrogenases?Characteristics, Design of Reaction Conditions, and Applications (pages 391-473): Jorg PetersChapter 10 Hydroxylation and Dihydroxylation (pages 475-533): Herbert L. HollandChapter 11 Flavin Monooxygenases-Uses as Catalysts for Baeyer?Villiger Ring Expansion and Heteroatom Oxidation (pages 535-587): David R. Kelly, Peter W. H. Wan and Jenny Tang

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Biotechnology: Biotransformations II, Volume 8b, Second Edition, Second Edition By
2000 | 537 Pages | ISBN: 3527283242 | PDF | 17 MB
Biotransformations have developed into an important tool of organic synthesis and most synthetic sequences will benefit from the use of a biotransformation step. This volume completes the collection of biotransformations presented in the Biotechnology series. Volumes 8 a and b provide a comprehensive guide to the established and emerging uses of enzymes, each chapter is devoted to a single class of transformation. The description of several bond forming reactions is followed by four chapters on structue and catalytic activity. Case studies of important industrial and synthetic applications round off the practical orientation of the book. Content: Chapter 1 Carbon?Carbon Bond Formation, Addition, Elimination and Substitution Reactions: 1 Carbon?Carbon Bond Formation Using Enzymes (pages 4-40): Anthony D. M. CurtisChapter 2 Lyases (pages 41-171): Jassem G. Mahdi and David R. KellyChapter 3 Halocompounds (pages 173-220): Gary K. Robinson, Simon A. Jackman and Jane StratfordChapter 4 Phosphorylation (pages 221-241): Simon JonesChapter 5 Enzymes in Carbohydrate Chemistry: Formation of Glycosidic Linkages (pages 243-274): Sabine L. Flitsch and Gregory M. WattChapter 6 Industrial Biotransformations (pages 276-294): Uwe T. BornscheuerChapter 7 Regioselective Oxidation of Aminosorbitol with Gluconobacter oxydans, Key Reaction in the Industrial 1?Deoxynojirimycin Synthesis (pages 295-311): Michael SchedelChapter 8 Engineering Microbial Pathways for Amino Acid Production (pages 313-332): Ian G. FotheringhamChapter 9 Biotechnological Production of Natural Aroma Chemicals by Fermentation Processes (pages 333-350): Jurgen RabenhorstChapter 10 Synthetic Applications of Enzyme?Catalyzed Reactions (pages 351-400): Jane McGregor?JonesChapter 11 Catalytic Antibodies (pages 402-490): George Michael Blackburn and Arnaud GarconChapter 12 Synthetic Enzymes-Artificial Peptides in Stereoselective Synthesis (pages 491-517): Paul A. Bentley

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Biotechnology: Environmental Processes I, Volume 11a, Second Edition By
1999 | 592 Pages | ISBN: 3527283218 | PDF | 25 MB
The first volume on environmental processes gives a profound overview on the biotechnology of wastewater. Part I deals with general aspects such as microbial metabolism, biofilms, analytical techniques, threshold values, methods of monitoring and regulations. Processes of wastewater treatment are presented in Part II: providing a lot of practical information origins and composition of wastewater from municipal, industrial and agricultural sources as well as aerobic and anaerobic processes in different types of reactors are described.Content: Chapter 1 Historical Development of Wastewater Treatment Processes (pages 4-16): Ludwig HartmannChapter 2 Bacterial Metabolism in Wastewater Treatment Systems (pages 17-53): Claudia Gallert and Josef WinterChapter 3 Nitrification and Denitrification?Microbial Fundamentals and Consequences for Application (pages 55-64): Dirk Zart, Ralf Stuven and Eberhard BockChapter 4 Autoaggregation of Microorganisms: Floes and Biofilms (pages 65-83): Jost Wingender and Hans?Curt FlemmingChapter 5 Nucleic Acid?Based Techniques for Analyzing the Diversity, Structure, and Dynamics of Microbial Communities in Wastewater Treatment (pages 85-108): Andreas Schramm and Rudolf AmannChapter 6 Analytical Parameters for Monitoring of Wastewater Treatment Plants (pages 109-123): Helmut Kroiss and Karl SvardalChapter 7 Monitoring of Environmental Processes with Biosensors (pages 125-139): Monika Reiss and Winfried HartmeierChapter 8 Laws, Statutory Orders and Directives on Waste and Wastewater Treatment (pages 141-158): Peter NisipeanuChapter 9 Municipal Wastewater and Sewage Sludge (pages 159-189): Paul Koppe, Alfred Stozek and Volkmar NeitzelChapter 10 Industrial Wastewater Sources and Treatment Strategies (pages 191-215): Karl?Heinz Rosenwinkel, Ute Austermann?Haun and Hartmut MeyerChapter 11 Agricultural Waste and Wastewater Sources and Management (pages 217-238): Peter WeilandChapter 12 Biological Processes in Wetland Systems for Wastewater Treatment (pages 240-251): Peter Kuschk, Arndt Wie?ner and Ulrich StottmeisterChapter 13 Activated Sludge Process (pages 253-283): Rolf KayserChapter 14 Biological and Chemical Phosphorus Elimination (pages 285-319): Georg Schon and Norbert JardinChapter 15 Continuous Flow and Sequential Processes in Municipal Wastewater Treatment (pages 321-334): Eberhard Morgenroth and Peter A. WildererChapter 16 Design of Nitrification/Denitrification in Fixed Growth Reactors (pages 335-348): Bernd Dorias, Gunter Hauber and Peter BaumannChapter 17 Submerged Fixed?Bed Reactors (pages 349-363): Judith M. Schulz and Genannt MenningmannChapter 18 Experience with Biofilters in Wastewater Treatment (pages 365-372): Carin Sieker and Matthias BarjenbruchChapter 19 Special Aerobic Wastewater and Sludge Treatment Processes (pages 373-415): Udo Wiesmann and Judy LibraChapter 20 Modeling of Aerobic Wastewater Treatment Processes (pages 417-427): Mogens HenzeChapter 21 Metal Removal by Biomass: Physico?Chemical Elimination Methods (pages 430-452): Gerald Bunke, Peter Gotz and Rainer BuchholzChapter 22 Anaerobic Metabolism and its Regulation (pages 454-478): Michael J. McInerneyChapter 23 CSTR Reactors and Contact Processes in Industrial Wastewater Treatment (pages 479-491): Helmut Kroiss and Karl SvardalChapter 24 Fixed Film Stationary Bed and Fluidized Bed Reactors (pages 493-515): Hans?Joachim Jordening and Klaus BuchholzChapter 25 Possibilities and Potential of Anaerobic Wastewater Treatment Using Anaerobic Sludge Bed (ASB) Reactors (pages 517-526): Gatze Lettinga, Look W. Hulshoff Pol, Jules B. Van Lier and Grietje ZeemanChapter 26 Modeling of Biogas Reactors (pages 527-560): Herbert MarklChapter 27 Future Aspects?Cleaner Production (pages 561-577): Norbert Rabiger

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Biotechnology in Animal Feeds and Animal Feeding By
1995 | 358 Pages | ISBN: 3527300651 | PDF | 16 MB
With the dramatically rising sophistication of biological methods and products and the increasing use of recombinant DNA technology, now is an apt time to review the status of biotechnology in animal feeding. This book gives succinct yet comprehensive coverage of products of biotechnology and allied sciences used in animal feed and feeding industries. Particular emphasis is placed on: - Conservation and upgrading of feeds and feed components - Increasing the protein value of feeds - Antimicrobials - Microbial feed additives - Increasing the energy value of feeds. Moreover, increasing environmental concerns are reflected in chapters describing dietary products which may help to reduce environmental hazards from animal feeding enterprises. A discussion of social and legislative aspects relating to biotechnology and animal feeding rounds off this useful compilation of timely articles. Content: Chapter 1 Biotechnology in animal feeds and animal feeding: an overview (pages 1-15): Frederick George PerryChapter 2 Legislation and the legislative environment (pages 17-31): Philip T. Reeves , Trevor Doust, Jean E. Hollebone, Judy Thompson, David R. Williams, Toshirou Nonomura, Masakazu Goto, Woodrow M. Knight, Sharon A. Benz and William D. PriceChapter 3 Silage additives (pages 33-54): Keith K. Bolsen, Gilad Ashbell and J. M. WilkinsonChapter 4 Biological upgrading of feed and feed components (pages 55-70): Frantisek Zadrazil, Anil Kumar Puniya and Kishan SinghChapter 5 Transgenic plants with improved protein quality (pages 71-92): Susan B. Altenbach and Jeffrey A. TownsendChapter 6 Industrial amino acids in nonruminant animal nutrition (pages 93-113): Daniel Bercovici and Malcolm F. FullerChapter 7 Protected proteins and amino acids for ruminants (pages 115-141): Charles G. SchwabChapter 8 Antibacterials in poultry and pig nutrition (pages 143-172): Gordon D. RosenChapter 9 Ionophores and antibiotics in ruminants (pages 173-204): T. G. NagarajaChapter 10 Microbial probiotics for pigs and poultry (pages 205-231): Stanislava Stavric and Ervin T. KornegayChapter 11 Oligosaccharide feed additives (pages 233-245): Pierre F. Monsan and Francois PaulChapter 12 Microbial feed additives for pre?ruminants (pages 247-258): Kyle E. Newman and Kate A. JacquesChapter 13 Microbial feed additives for ruminants (pages 259-278): C. James NewboldChapter 14 Transgenic plants with improved energy characteristics (pages 279-293): Claire Halpin, Geoffrey A. Foxon and P. Anthony FentemChapter 15 Dietary enzymes for increasing energy availability (pages 295-309): Hadden Graham and Derick BalnaveChapter 16 Biotechnology in the treatment of animal manure (pages 311-327): Marleen Vande Woestyne and Willy VerstraeteChapter 17 Feed additives and other interventions for decreasing methane emissions (pages 329-349): Christian Van Nevel and Daniel Demeyer

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Biotechnology: Special Processes, Volume 10, Second Edition By
2001 | 611 Pages | ISBN: 352728320X | PDF | 11 MB
Volume 10 on Special Processes completes the Second Edition of the Biotechnology series providing an overview on innovative and special fields of biotechnology. In the other volumes of the series many larger areas of biotechnology are treated with respect to principal aspects, while Volume 10 covers more specialized topics. Areas which are anticipated to have a highly promising future are nanobiotechnology, bioelectrochemical fuel cells, bacteriorhodopsin and other substances used as information systems. Further fields - although small - are of current importance such as marine biotechnology, biotechnology in phytopathology, biotechnology with extremophiles, and biotechnology with protozoa. Volume 10 enables the reader to access these and further special fields of biotechnology. The proven quality of extensive references provides a good basis to gain further insight into the fields.Content: Chapter 1 Bioelectrochemical Fuel Cells (pages 5-23): Dieter SellChapter 2 Maintenance of Cell Cultures?with Special Emphasis on Eukaryotic Cells (pages 26-40): Claudia BardouilleChapter 3 New Methods of Screening in Biotechnology (pages 41-60): Klaus Frobel and Susanne MetzgerChapter 4 Biocatalysis under Extreme Conditions (pages 61-103): Costanzo Bertoldo, Ralf Grote and Garabed AntranikianChapter 5 Biotechnology with Cyanobacteria and Microalgae (pages 105-136): Otto Pulz, Karl Scheibenbogen and Wolfgang Gro?Chapter 6 Biotechnology with Protozoa (pages 137-149): Arno TiedtkeChapter 7 Biotechnology of Coal (pages 152-189): Jurgen Klein, Rene Fakoussa, Udo Holker, Martin Hofrichter, Helmut Schmiers, Christoph Sinder and Alexander SteinbuchelChapter 8 Microbial Leaching of Metals (pages 191-224): Helmut BrandlChapter 9 Accumulation and Transformation of Metals by Microorganisms (pages 225-264): Geoffrey M. GaddChapter 10 Microbial Corrosion and its Inhibition (pages 265-316): Wolfgang SandChapter 11 Vitamins and Related Compounds: Microbial Production (pages 318-340): Sakayu ShimizuChapter 12 Biochemistry of Polyketide Synthases (pages 341-372): Rajesh S. Gokhale and Dipika TutejaChapter 13 Biotechnological Production of Terpenoid Flavor and Fragrance Compounds (pages 373-422): Jens Schrader and Ralf G. BergerChapter 14 New Degradable Resins (pages 423-438): Alexander SteinbuchelChapter 15 Marine Biotechnology (pages 440-484): Ulrike Lindequist and Thomas SchwederChapter 16 Biotechnology in Plant Protection (pages 485-506): Frank Niepold and Klaus RudolphChapter 17 Biotechnology in Space (pages 507-521): Heide SchnablChapter 18 Biotechnology in the Pulp and Paper Industry (pages 523-546): Liisa Viikari, Mana Tenkanen and Anna SuurnakkiChapter 19 Microencapsulation?Based Cell Therapy (pages 547-571): Ulrich Zimmermann, Hubert Cramer, Anette Jork, Frank Thurmer, Heiko Zimmermann, Gunter Fuhr, Christian Hasse and Matthias RothmundChapter 20 Comments on Other Fields of Biotechnology (pages 573-586): Hans?Jurgen Rehm

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Bipolar Psychopharmacotherapy: Caring for the Patient By
2006 | 400 Pages | ISBN: 0470856076 | PDF | 10 MB
Bipolar disorder is often not recognized as an illness, and people may suffer for years before it is properly diagnosed and treated. Like diabetes or heart disease, bipolar disorder is a long-term illness that must be carefully managed throughout a person's life. Pharmacotherapy is central to the acute treatment and long-term management of the disorder and as there are several classes of drugs, which are often prescribed concurrently, treatment issues are complex. This essential reference work examines major pharmacological treatments in the different phases of bipolar disorder.Chapters are devoted to commonly use pharmacological treatments with a critical review of the existing literature. Each chapter includes information not only on studies that have been published but also on new treatments that have been reported in peer reviewed scientific meetings. Bipolar Psychopharmacotherapy covers both pharmacotherapy and the role of psychotherapy, psychoeducation and social approaches to provide a broad integrative philosophy of care for bipolar patients. Extensive coverage is given to special management issues such as the care of women with bipolar disorder, children and the elderly, as well as bipolar depression and suicide prevention. With contributions from the pioneers in the field and an expert editor team, Bipolar Psychopharmacotherapy provides psychiatrists and all mental health practitioners with an invaluable guide to the management of these complex patients. From the reviews:"If a colleague were to ask me, "What would you recommend I read if I want to become a real expert on bipolarity?" I would respond 'Bipolar Psychopharmacotherapy: Caring for the Patient'." JOURNAL OF BIPOLAR DISORDERS "... a very useful reference on the pharmacological treatment of bipolar disorder that is written in a very practical and user-friendly format... a must for anyone dealing with patients with bipolar disorder." DOODY'S HEALTH SERVICES "... a multifaceted text with broad clinical value... recommended as an in-office reference for the practicing physician who treats the bipolar patients... to all Health Science libraries as a general reference text." THE ELECTRIC REVIEW Content: Chapter 1 The Scope of Bipolar Disorders (pages 1-8): Hagop S. AkiskalChapter 2 Lithium Treatment: Focus on Long?Term Prophylaxis (pages 9-26): Mogens Schou and Paul GrofChapter 3 Valproate: Clinical Pharmacological Profile (pages 27-42): Charles L. Bowden and Vivek SinghChapter 4 Pharmacological Profile and Clinical Utility of Lamotrigine in Bipolar Disorders (pages 43-62): David J. Muzina and Joseph R. CalabreseChapter 5 Carbamazepine, Other Anticonvulsants and Augmenting Agents (pages 63-83): Heinz GrunzeChapter 6 Olanzapine in Treatment for Bipolar Disorder (pages 85-103): Mauricio Tohen, Giedra Campbell and Daniel LinChapter 7 Haloperidol and Risperidone in Mania (pages 105-123): John CooksonChapter 8 A Comparison of "Second Generation Antipsychotics" in the Treatment for Bipolar Disorder: Focus on Clozapine, Quetiapine, Ziprasidone and Aripiprazole (pages 125-134): Paul E. Keck and Susan L. McElroyChapter 9 Complex Combination Therapy: The Evolution Toward Rational Polypharmacy in Lithium?Resistant Bipolar Illness (pages 135-167): Robert M. Post, Andrew M. Speer and Gabriele S. LeverichChapter 10 The Primacy of Mania (pages 169-192): Athanasios KoukopoulosChapter 11 Diagnostic and Clinical Management Approaches to Bipolar Depression, Bipolar II and Their Comorbidities (pages 193-234): Giulio Perugi, S. Nassir Ghaemi and Hagop AkiskalChapter 12 Bipolarity in Women: Therapeutic Issues (pages 235-277): Susan L. McElroy, Lesley M. Arnold and Lori L. AltshulerChapter 13 Pediatric Bipolar Disorder: The Promise of Psychopharmacotherapy (pages 279-299): Joseph BiedermanChapter 14 Treatment for Bipolar Disorder in Older Adults (pages 301-311): Kenneth I. ShulmanChapter 15 Psychosocial Interventions in Bipolar Disorders: Rationale and Effectiveness (pages 313-332): David J. MiklowitzChapter 16 The Pivotal Role of Psychoeducation in the Long?Term Treatment of Bipolar Disorder (pages 333-345): Francesc Colom and Eduard VietaChapter 17 The Role of Treatment Setting in the Pharmacotherapy of Bipolar Disorder (pages 347-352): Jean?Michel AzorinChapter 18 Suicide Prevention (pages 353-365): Zoltan RihmerChapter 19 Principles of Caring for Bipolar Patients (pages 367-387): Hagop S. Akiskal and Kareen K. Akiskal

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Bistatic Radar: Emerging Technology By
2008 | 408 Pages | ISBN: 0470026316 | PDF | 17 MB
The impact of bistatic radar technology on remote sensing is increasing as bistatic systems cross the theoretical threshold into practical embodiment. The wide spectrum of radar applications, including space exploration, defence, transport, aerospace, and meteorology, provides persistent impetus for this progress. This book is dedicated to the more advanced studies in bistatic radar which are currently the subject of intensive research activity and development. With contributions from the leading experts in the field of bistatic radar research, this book collates the latest developments in the field focusing particularly on bistatic synthetic aperture radar (BSAR) and passive bistatic radar systems (PBRS). Within these two areas the text: addresses the main BSAR topologies: spaceborne BSAR, airborne BSAR and space-surface BSAR; analyses the resurgent interest in, and practical applications of, PBRS; introduces passive BSAR technology; covers research of systems used in aircraft detection and tracking, and passive radar remote sensing of the ionosphere and the upper atmosphere. Bistatic Radar: Emerging Technology is an invaluable resource for practising engineers and researchers involved in the design and implementation of advanced bistatic radar systems in aerospace, communications, defence, transport and meteorology. Following on from Bistatic Radar: Principles and Practice it is also a comprehensive reference on the latest research for postgraduate students taking specialist courses in radar technology.Content: Chapter 1 Fundamentals of Bistatic Synthetic Aperture Radar (pages 1-26): Antonio MocciaChapter 2 Spaceborne Bistatic Synthetic Aperture Radar (pages 27-65): Antonio Moccia and Marco D'ErricoChapter 3 Bistatic SAR for Earth Observation (pages 67-93): A. Moccia and M. D'erricoChapter 4 Spaceborne Interferometric and Multistatic SAR Systems (pages 95-158): Gerhard Krieger and Alberto MoreiraChapter 5 Airborne Bistatic Synthetic Aperture Radar (pages 159-213): Pascale Dubois?Fernandez, Hubert Cantalloube, Bernard Vaizan, Gerhard Krieger and Alberto MoreiraChapter 6 Space?Surface Bistatic SAR (pages 215-246): Mikhail Cherniakov and Tao ZengChapter 7 Passive Bistatic Radar Systems (pages 247-313): Paul E. Howland, Hugh D. Griffiths and Chris J. BakerChapter 8 Ambiguity Function Correction in Passive Radar: DTV?T Signal (pages 315-337): Mikhail CherniakovChapter 9 Passive Bistatic SAR with GNSS Transmitters (pages 339-361): Mikhail Cherniakov and Tao ZengChapter 10 Ionospheric Studies (pages 363-387): John D. Sahr

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Blended Learning in Higher Education: Framework, Principles, and Guidelines By D. Randy Garrison, Norman D. Vaughan(auth.)
2007 | 245 Pages | ISBN: 0787987700 | PDF | 3 MB
This groundbreaking book offers a down-to-earth resource for the practical application of blended learning in higher education as well as a comprehensive examination of the topic. Well-grounded in research, Blended Learning in Higher Education clearly demonstrates how the blended learning approach embraces the traditional values of face-to-face teaching and integrates the best practices of online learning. This approach has proven to both enhance and expand the effectiveness and efficiency of teaching and learning in higher education across disciplines. In this much-needed book, authors D. Randy Garrison and Norman D. Vaughan present the foundational research, theoretical framework, scenarios, principles, and practical guidelines for the redesign and transformation of the higher education curriculum. Blended Learning in Higher EducationOutlines seven blended learning redesign principles Explains the professional development issues essential to the implementation of blended learning designs Presents six illustrative scenarios of blended learning design Contains practical guidelines to blended learning redesign Describes techniques and tools for engaging students Content: Chapter 1 Introduction (pages 1-11): Chapter 2 Community of Inquiry and Blended Learning (pages 13-30): Chapter 3 Designing Blended Learning to Create a Community of Inquiry (pages 31-48): Chapter 4 Community of Inquiry for Faculty Development (pages 49-67): Chapter 5 Scenarios (pages 69-83): Chapter 6 Guidelines (pages 85-104): Chapter 7 Strategies and Tools (pages 105-141): Chapter 8 The Future (pages 143-155):

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Blood-Brain Barriers: From Ontogeny to Artificial Interfaces, Volume 1 By
2006 | 774 Pages | ISBN: 3527310886 | PDF | 8 MB
This first handbook to integrate developmental and cellular aspects combines the different structural and functional features involved in the regulation of brain perfusion and neuronal function. It highlights pharmacological and biomedical applications with sections on drug delivery and disease-related states as well as explaining in detail the role of astrocytes, shown to be an essential link between neurons and cerebral blood vessels. In addition the book studies how the structural elements interact in response to the dynamics of neuronal activities, necessitating adaptive mechanism of the interface. A significant part of the book describes new approaches to how the barrier can be surmised for drug delivery and how it can be mimicked by artificial in vitro systems for drug testing. Finally, the involvement of the barrier in brain diseases is considered, focusing on inflammatory and neurodegenerative disorders of the brain. Covering basic knowledge as well as specific information dealing with very recent progress in blood-brain interface research, this book will be of interest to a broad audience. Content: Chapter 1 Development of the Blood?Brain Interface (pages 9-39): Britta EngelhardtChapter 2 Brain Angiogenesis and Barriergenesis (pages 41-59): Jeong Ae Park, Yoon Kyung Choi, Sae?Won Lee and Kyu?Won KimChapter 3 Microvascular Influences on Progenitor Cell Mobilization and Fate in the Adult Brain (pages 61-74): Christina Lilliehook and Steven A. GoldmanChapter 4 The Endothelial Frontier (pages 75-107): Hartwig WolburgChapter 5 Pericytes and Their Contribution to the Blood?Brain Barrier (pages 109-127): Markus RamsauerChapter 6 Brain Macrophages: Enigmas and Conundrums (pages 129-165): Frederic Mercier, Sebastien Mambie and Glenn I. HattonChapter 7 The Microglial Component (pages 167-188): Ingo Bechmann, Angelika Rappert, Josef Priller and Robert NitschChapter 8 The Bipolar Astrocyte: Polarized Features of Astrocytic Glia Underlying Physiology, with Particular Reference to the Blood?Brain Barrier (pages 189-208): N. Joan AbbottChapter 9 Responsive Astrocytic Endfeet: The Role of AQP4 in BBB Development and Functioning (pages 209-236): Grazia P. Nicchia, Beatrice Nico, Laura M. A. Camassa, Maria G. Mola, Domenico Ribatti, David C. Spray, Alejandra Bosco, Maria Svelto and Antonio FrigeriChapter 10 The Role of Fibroblast Growth Factor 2 in the Establishment and Maintenance of the Blood?Brain Barrier (pages 237-246): Bernhard ReussChapter 11 Cytokines Interact with the Blood?Brain Barrier (pages 247-264): Weihong Pan, Shulin Xiang, Hong Tu and Abba J. KastinChapter 12 Insulin and the Blood?Brain Barrier (pages 265-285): William A. Banks and Wee Shiong LimChapter 13 Glucocorticoid Hormones and Estrogens: Their Interaction with the Endothelial Cells of the Blood?Brain Barrier (pages 287-312): Jean?Bernard DietrichChapter 14 Metalloproteinases and the Brain Microvasculature (pages 313-334): Dorothee Krause and Christina LohmannChapter 15 Modeling the Blood?Brain Barrier (pages 335-355): Romeo Cecchelli, Caroline Coisne, Lucie Dehouck, Florence Miller, Marie?Pierre Dehouck, Valerie Buee?Scherrer and Benedicte DehouckChapter 16 Induction of Blood?Brain Barrier Properties in Cultured Endothelial Cells (pages 357-374): Alla Zozulya, Christian Weidenfeller and Hans?Joachim GallaChapter 17 Artificial Blood?Brain Barriers (pages 375-401): Luca Cucullo, Emily Oby, Kerri Hallene, Barbara Aumayr, Ed Rapp and Damir JanigroChapter 18 In Silico Prediction Models for Blood?Brain Barrier Permeation (pages 403-428): Gerhard F. Ecker and Christian R. NoeChapter 19 The Blood?Brain Barrier: Roles of the Multidrug Resistance Transporter P?Glycoprotein (pages 429-461): Sandra Turcotte, Michel Demeule, Anthony Regina, Chantal Fournier, Julie Jodoin, Albert Moghrabi and Richard BeliveauChapter 20 Targeting of Neuropharmaceuticals by Chemical Delivery Systems (pages 463-500): Nicholas Bodor and Peter BuchwaldChapter 21 Drug Delivery to the Brain by Internalizing Receptors at the Blood?Brain Barrier (pages 501-520): Pieter J. Gaillard, Corine C. Visser and Albertus (Bert) G. de BoerChapter 22 Blood?Brain Transfer and Metabolism of Oxygen (pages 521-549): Albert GjeddeChapter 23 Functional Brain Imaging (pages 551-599): Gerald A. DienelChapter 24 Inflammatory Response of the Blood?Brain Interface (pages 601-618): Pedro M. Faustmann and Claus G. HaaseChapter 25 Stroke and the Blood?Brain Interface (pages 619-647): Marilyn J. CipollaChapter 26 Diabetes and the Consequences for the Blood?Brain Barrier (pages 649-669): Arshag D. MooradianChapter 27 Human Parasitic Disease in the Context of the Blood?Brain Barrier - Effects, Interactions, and Transgressions (pages 671-700): Mahalia S. Desruisseaux, Louis M. Weiss, Herbert B. Tanowitz, Adam Mott and Danny A. MilnerChapter 28 The Blood Retinal Interface: Similarities and Contrasts with the Blood?Brain Interface (pages 701-724): Tailoi Chan?Ling

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Bone Marrow Pathology, Third Edition By Barbara J. Bain, David M. Clark, Irvin A. Lampert, Bridget S. Wilkins(auth.)
2001 | 508 Pages | ISBN: 0632055782 | PDF | 23 MB
Content: Chapter 1 The Normal Bone Marrow (pages 1-50): Chapter 2 Special Techniques Applicable to Bone Marrow Diagnosis (pages 51-89): Chapter 3 Infection and Reactive Changes (pages 90-140): Chapter 4 Acute Myeloid Leukaemia, the Myelodysplastic Syndromes and Histiocytic Neoplasms (pages 141-190): Chapter 5 Chronic Myeloproliferative and Myeloproliferative/Myelodysplastic Disorders (pages 191-230): Chapter 6 Lymphoproliferative Disorders (pages 231-331): Chapter 7 Multiple Myeloma and Related Disorders (pages 332-359): Chapter 8 Disorders of Erythropoiesis, Granulopoiesis and Thrombopoiesis (pages 360-390): Chapter 9 Miscellaneous Disorders (pages 391-429): Chapter 10 Metastatic Tumours (pages 430-461): Chapter 11 Diseases of Bone (pages 462-473):

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Bovine Genomics By
2012 | 281 Pages | ISBN: 0813821223 | PDF | 3 MB
The genetic information being unlocked by advances in genomic and high throughput technologies is rapidly revolutionizing our understanding of developmental processes in bovine species. This information is allowing researchers unprecedented insight into the genetic basis of key traits. Bovine Genomics is the first book to bring together and synthesize the information learned through the bovine genome sequencing project and look at its practical application to cattle and dairy production. Bovine Genomics opens with foundational chapters on the domestication of cattle and traditional Mendelian genetics. Building on these chapters, coverage rapidly moves to quantitative genetics and the advances of whole genome technologies. Significant coverage is given to such topics as epigenetics, mapping quantitative trail loci, genome-wide association studies and genomic selection in cattle breeding. The book is a valuable synthesis of the field written by a global team of leading researchers.Providing wide-ranging coverage of the topic, Bovine Genomic, is an essential guide to the field. The basic and applied science will be of use to researchers, breeders, and advanced students.Content: Chapter 1 The Origins of Cattle (pages 1-10): Matthew D. Teasdale and Daniel G. BradleyChapter 2 Mendelian Inheritance in Cattle (pages 11-19): Frank W. NicholasChapter 3 Genetics of Coat Color in Cattle (pages 20-33): Sheila M. SchmutzChapter 4 From Quantitative Genetics to Quantitative Genomics: A Personal Odyssey (pages 34-50): Morris SollerChapter 5 Cartography of the Bovine Genome (pages 51-62): James E. WomackChapter 6 History of Linkage Mapping the Bovine Genome (pages 63-74): Stephanie D. McKay and Robert D. SchnabelChapter 7 Bovine X and Y Chromosomes (pages 75-100): F. Abel Ponce de Leon and Wansheng LiuChapter 8 Cattle Comparative Genomics and Chromosomal Evolution (pages 101-108): Denis M. LarkinChapter 9 Sequencing the Bovine Genome (pages 109-122): Kim C. Worley and Richard A. GibbsChapter 10 Bovine Genome Architecture (pages 123-143): David L. AdelsonChapter 11 Bovine Epigenetics and Epigenomics (pages 144-168): Xiuchun (cindy) TianChapter 12 Mapping Quantitative Trait Loci (pages 169-191): Joel I. WellerChapter 13 Genome?Wide Association Studies and Linkage Disequilibrium in Cattle (pages 192-210): M. E. Goddard and B. J. HayesChapter 14 Genomic Selection in Beef Cattle (pages 211-233): Jeremy F. Taylor, Stephanie D. McKay, Megan M. Rolf, Holly R. Ramey, Jared E. Decker and Robert D. SchnabelChapter 15 Impact of High?Throughput Genotyping and Sequencing on the Identification of Genes and Variants Underlying Phenotypic Variation in Domestic Cattle (pages 234-258): Michel Georges

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Bovine Surgery and Lameness, Second Edition By
2005 | 287 Pages | ISBN: 1405123826 | PDF | 3 MB
Bovine surgery is both challenging and complicated. Not only does the surgeon have to decide whether surgery is economically justified, but surgery often has to be performed in a sub-optimal environment. Following on from the worldwide success of the first edition, this new edition continues to act as a step-by-step guide to standard surgical techniques. Now with two new authors from Switzerland and North America, both the text and illustrations have been considerably expanded. In addition, special attention is given to issues relating to peri-operative analgesia and animal welfare, food safety, and drug dosages. Maintains the popular concise and accessible format of the first edition - perfect for on-the-field work; Two additional authors, with world renowned expertise in bovine surgery and lameness; Detailed instruction on the basics of effective surgery - proper instrumentation, asepsis, effective anaesthesia and essential techniques; Much more information on lameness, as well as numerous new line drawings to aid instruction.Content: Chapter 1 General Considerations and Anaesthesia (pages 11-63): Chapter 2 Head and Neck Surgery (pages 64-84): Chapter 3 Abdominal Surgery (pages 85-149): Chapter 4 Female Urinogenital Surgery (pages 150-167): Chapter 5 Teat Surgery (pages 168-177): Chapter 6 Male Urinogenital Surgery (pages 178-207): Chapter 7 Lameness (pages 208-268):

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Breakthroughs in Literacy: Teacher Success Stories and Strategies, Grades K-8 By Susan E. Israel(auth.)
2009 | 212 Pages | ISBN: 047037182X | PDF | 3 MB
Teachers share advice on creating successful literacy classrooms for all students, including those who struggle This much-needed resource is filled with lively and inspiring stories from teachers who overcame challenges with underperforming and struggling learners-many of them special needs students-to make significant breakthroughs in reading and writing instruction. The teachers reveal their trials, errors, and triumphs in how they discovered particular instructional strategies or incorporated modeling and motivational techniques that best addressed students' learning needs and opened a path to success. Compelling and absorbing, the book includes unusual and often surprising approaches for connecting with students, including books that made a difference. Offers wisdom, inspiration, and guidance on working with varied students to improve reading and writing skills Contains 29 stories from real-world teachers who have had success in teaching literacy Summary sections focus on key breakthrough strategies, lessons learned, reflection questions, actions tips, and recommended resources Describes effective modeling, motivational, and engagement practices Content:

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Bribery and Corruption: Navigating the Global Risks By Brian Loughman, Richard Sibery(auth.)
2012 | 417 Pages | ISBN: 1118011368 | PDF | 4 MB
As businesses continue to expand globally into new and emerging markets, bribery and corruption risks have increased exponentially. Bribery and Corruption offers a comprehensive look at this growing problem, and at the Foreign Corrupt Practices Act (FCPA) and other international anti-bribery and corruption conventions. Presenting hypothetical examples of situations companies will face, along with practical solutions, the book offers detailed global guidance on a region and country-specific basis. The FCPA prohibits US companies and their subsidiaries from bribing foreign officials, either directly or indirectly through intermediaries, for the purpose of obtaining or retaining business. It also requires companies to keep accurate records of all business transactions and maintain an effective system of internal accounting controls. Internationally, the Organization of Economic Cooperation and Development's (OECD's) anti-bribery convention has been adopted by 38 countries and creates legally binding standards related to bribery of foreign public officials. Written by renowned accounting fraud experts Richard A. Sibery and Brian P. Loughman, and providing an introduction and overview of the Foreign Corrupt Practices Act (FCPA) and international bribery laws, Bribery and Corruption considers: How to conduct FCPA risk assessments and investigations How to consider FCPA specific financial controls How to implement an FCPA compliance program and how to measure FCPA compliance The risk of bribery and corruption continues to be an area of concern for companies around the world, but armed with Bribery and Corruption, it is easier than ever to understand the challenges that exist and how to deal with them.Content: Chapter 1 Introduction (pages 1-7): Chapter 2 Overview of FCPA (pages 9-27): Chapter 3 The U.K. Bribery Act and International Bribery and Corruption Initiatives (pages 29-45): Chapter 4 Compliance Programs (pages 47-73): Chapter 5 Policies and Procedures (pages 75-112): Chapter 6 Risk Assessments (pages 113-127): Chapter 7 Monitoring (pages 129-151): Chapter 8 Anti?Corruption Due Diligence (pages 153-175): Chapter 9 Investigations (pages 177-224): Chapter 10 Regional Considerations for Bribery and Corruption Risks (pages 225-293): Chapter 11 Industry Considerations for Bribery and Corruption Risks (pages 295-385):

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