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Nanomedicine in Treatment of Diseases (Learning Materials in Biosciences) by Bushra Akhtar, Faqir Muhammad, Ali Sharif
English | January 28, 2024 | ISBN: 9819976251 | 413 pages | PDF | 13 Mb
Nanomedicine biotechnology is applied to and used to study drug development, working mechanisms, diagnosis, and therapies. This textbook particularly written for biomedical applications of nanomedicine covers the whole range of disease treatments related to nanomedicine. This book serves the purpose of highlighting the current advancements of nanomedicines-based regimens which may be employed in disease treatment while it also contains the fundamental knowledge for biomedical researchers from all levels. Each chapter starts with an introduction/theory into the specified approaches for various disease states followed by detailed discussions for a comprehensive understanding. This book best suits advanced level students, but also provides an excellent updated material for researchers and healthcare workers related to nanomedicine and diseases treatment.
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Nanoparticles in Cancer Therapy: Innovations and Clinical Applications
by Edited by Neelam Thakur and Prudhvi Lal Bhukya
English | 2025 | ISBN: 1032849177 | 345 pages | True PDF EPUB | 59.49 MB
This book presents the role of nanoparticles in cancer therapy, emphasizing their innovative applications across treatment, diagnosis and the development of therapeutic strategies. The first section of the book describes the applications of nanoparticles in cancer vaccines and gene therapy. It features discussions on polymeric nanoparticles as nanovaccine carriers, membrane-based nano-vaccines for immunotherapy and gene therapy techniques employing nanoparticles. The second section presents advanced nanomedicine approaches, specifying the role of chemodynamic nanoparticles in cancer theranostics, the application of low-dimensional nanomaterials and emerging strategies against drug resistance. Additionally, it explores nanotechnology in radiation therapy, phototherapy modalities and bioengineered virus-like nanoparticles for diagnostics and therapeutics. The last section reviews the clinical applications and prospects, examining theranostic nanoparticles, the clinical translation of nanomedicine and the current limitations of cancer nanotherapy. It also addresses future directions in nanoparticle application, and examines the genotoxicity, immunotoxicity, cytotoxicity assessments, safety profiles, targeted drug delivery, and their role in viral oncogenesis. This book is a useful resource for researchers, clinicians and students in the fields of oncology and nanotechnology.
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Vladislav Ilves, "Nanopowders of Metal Oxides and Fluorides: Preparation, Properties, and Applications"
English | 2022 | ISBN: 9814968382 | PDF | pages: 713 | 442.4 mb
One of the directions of nanotechnology is the production of nanopowders (NPs). Nanopowders, according to the currently widely used classification of nanomaterials, belong to zero-dimensional systems in which the limitation of wave functions occurs in all three directions. Biological methods are considered the most environmentally friendly way to synthesize NPs, but the possibility of biological contamination with mutated microorganisms cannot be ruled out.
This book presents a new method for producing simple and complex metal oxide and fluoride NPs, based on the "evaporation-condensation" process using pulsed electron beam evaporation. It presents the results of more than 10 years of study of the characteristics of NPs produced using the aforementioned method. This eco-friendly method ensures the production of clean NPs, which are mesoporous and suitable for use in various applications such as medicine, spintronics, optoelectronics, dosimeters, photocatalysis, semiconductors, and ultraviolet and blue lasers. Importantly, these NPs have the potential to be used as a drug delivery system and in the creation of new nanostructures that do not contain noble metals. The book will be useful for the researchers in macromolecular science, nanotechnology, chemistry, biology, and medicine, especially those with an interest in drug delivery or cancer therapy.
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Neural networks for hydrological modelling By Robert J Abrahart; Pauline E Kneale; Linda M See
2004 | 302 Pages | ISBN: 0203024117 | PDF | 5 MB
''With contributions from international professionals and researchers, this book is one of the first texts to address the emerging field of Neuroadaptive Systems and presents the state of the art developments in the field. It discusses neuroscience and human factors, as well as brain activity measurement. Topics covered include operator functional state (OFS) and neuroadaptive systems; psychological constructs versus neuronal mechanisms; object recognition versus object-directed grasping; mental fatigue, sleeplessness, and neural mechanisms of control; and attentional network and error related negativity associated with sleep deprivation''--
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Merja Kytö, Mats Rydén, Erik Smitterberg, "Nineteenth-Century English: Stability and Change"
English | 2006 | pages: 317 | ISBN: 0521861063, 0521117240 | PDF | 2,5 mb
This volume of Studies in English Language focuses on the nineteenth century, an important period of both stability and change for the English language. Through ten detailed case studies, it highlights the relationships between English, its users, and nineteenth-century society, looking particularly at gender differences and variation across genres. It also discusses major structural aspects of nineteenth-century English, such as nouns, verbs and adjectives, and Germanic vs. Romance vocabulary. Although the nineteenth century is often viewed as a relatively stable period in the development of the language, this volume shows the 1800s to be a time of significant change, some of which continued into the twentieth century. By making comparisons possible with both earlier and later periods, it makes an important contribution to our overall understanding of the history of the English language.
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Stathis Gourgouris, "Nothing Sacred"
English | ISBN: 0231215150 | 2024 | 360 pages | PDF | 11 MB
Nothing Sacred makes a bold call for reconceptualizing the projects of humanism and democracy as creative sources of emancipatory meaning, from the immediate political sphere to the farthest reaches of planetary ways of living.
Restaging Aristotle's classic notion of the "political animal" in broad historical and geographical frames, Stathis Gourgouris explores the autopoietic capacities of human-being in society, while developing new frameworks of anticolonial humanism and radical democracy as the only worthy adversaries of neoliberal capitalism.
This reconfigured anthropological horizon enables us to imagine new ways of living by learning to pursue a radical politics of autonomy and a planetary vision that upholds life-affirming coexistence and equal sharing against the fetishism of hierarchy and servitude, money and technologic, sovereignty and endless growth.
Written with daring, erudition, and anarchic contestation, this book seeks the political through a poetic perspective.
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Nutrition and Gastrointestinal Disease By Mark H. DeLegge MD, FACG, AGAF, FASGE (auth.)
2008 | 334 Pages | ISBN: 1588298086 | PDF | 5 MB
Nutritional support of people with gastrointestinal impairment is critical to treatment and ultimately successful management. As such, gastroenterologists should be experts in nutrition and knowledgeable about the affects of nutrition on disease management. Nutritional and Gastrointestinal Disease fulfills that need, serving as a hands-on, practical reference in nutrition support for the clinical gastroenterologist and other clinicians with similar interests. The volume offers expert nutritional knowledge and management ideas as well as methodology for combating problems such as short bowel syndrome, inflammatory bowel disease, celiac disease and obesity. Renowned authorities also investigate nutrition's influence on such issues as liver failure and acute pancreatitis. While gastroenterology training programs around the world remain deficient in their nutrition curriculum, Nutritional and Gastrointestinal Disease provides a comprehensive and groundbreaking support for clinical gastroenterologists.
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Obstetric Medicine: A Problem-Based Approach By Catherine Nelson-Piercy MA, FRCP, Joanna Girling MA, MRCP, FRCOG (auth.)
2007 | 188 Pages | ISBN: 1846285631 | PDF | 1 MB
Medical problems in pregnancy are responsible for much maternal and fetal morbidity and mortality. This book is a collection of exam questions and case studies which illustrates both common and more unusual problems in obstetric medicine. Using a problem-based approach to both teach and test knowledge, it incorporates many different approaches to obstetric medicine, in Q & A format. The 'Extended Matched Questions' section covers the breadth of theoretical knowledge. The 'Short Answers / Data Interpretation' section requires a systematic approach to a clinical problem. Most of the case reports are based on real cases and all are accompanied by a brief literature review to further broaden the learning experience. This book is a valuable learning and exam preparation guide which enables trainees and consultants to test themselves using the different methods, as well as read about medical problems in pregnancy they may not yet have encountered.
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Bohang Chen, "On the Riddle of Life: A Historico-Logical Study of Vitalism "
English | ISBN: 3031706897 | 2024 | 317 pages | PDF | 5 MB
This book presents a historico-logical study of vitalism. It begins by uncovering previously unknown doctrines of vitalism from the history of science―encompassing biological, physical, and social sciences―and then subjects these doctrines to a thorough logical analysis. Through this process, the book offers a unified conceptual framework to understand the major doctrines of vitalism in the history of science, ultimately relating vitalism to the question of life. Following the classical methodological approach endorsed by Immanuel Kant, nineteenth-century philosopher-scientists like Ernst Mach, and early-twentieth-century logical analysts, including logical empiricists, British analysts, pragmatists, Husserlian phenomenologists, and neo-Kantians, this work provides unconventional and valuable perspectives on vitalism and the riddle of life, appealing to a broad audience, including scientists, historians, and philosophers of science, particularly those from biological backgrounds.
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Operative Neuromodulation: Volume 1: Functional Neuroprosthetic Surgery. An Introduction By Damianos. E. Sakas, I. G. Panourias, B. A. Simpson, E. S. Krames (auth.), Damianos E. Sakas, Brian A. Simpson, Elliot S. Krames (eds.)
2007 | 486 Pages | ISBN: 321133078X | PDF | 9 MB
Neuromodulation is a rapidly evolving multidisciplinary biomedical and biotechnological field. The two volumes present the state-of-the-art in established and emerging applications for pain, spasticity, movement disorders, bladder and bowel dysfunction, cardiovascular disease, epilepsy, psychiatric illness, impairment of hearing and vision, and computational neuromodulation. Experts describe the neural networks involved and the appropriate surgical approaches, provide clinical guidelines, technical descriptions of implanted devices, proposals for refinements and personal views on future prospects of the field. The immense therapeutic potential is highlighted which arises from the close collaboration of biomedical scientists and biotechnological engineers in this area and signifies the transition from the conventional "resective" surgery to functional neuroprosthetic surgery (Vol. I) and neural networks surgery (Vol. II) which uses neuro-engineering to improve impaired neural function.Volume I describes techniques and procedures applied in internal contact with non-neural tissues surrounding the nervous system (dura or cerebrospinal fluid), as in the case of epidural stimulation for pain, etc. or intrathecal drug application for the treatment of spasticity and pain. There is also a special section on non-invasive functional neuroprosthetic systems, which are usually applied by transcutaneous contact with the nervous system.
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Operative Neuromodulation: Volume 2: Neural Networks Surgery By Damianos E. Sakas, I. G. Panourias, B. A. Simpson (auth.), Damianos E. Sakas, Brian A. Simpson (eds.)
2007 | 590 Pages | ISBN: 3211330801 | PDF | 11 MB
Neuromodulation is a rapidly evolving multidisciplinary biomedical and biotechnological field. The two volumes present the state-of-the-art in established and emerging applications for pain, spasticity, movement disorders, bladder and bowel dysfunction, cardiovascular disease, epilepsy, psychiatric illness, impairment of hearing and vision, and computational neuromodulation. Experts describe the neural networks involved and the appropriate surgical approaches, provide clinical guidelines, technical descriptions of implanted devices, proposals for refinements and personal views on future prospects of the field. The immense therapeutic potential is highlighted which arises from the close collaboration of biomedical scientists and biotechnological engineers in this area and signifies the transition from the conventional "resective" surgery to functional neuroprosthetic surgery (Vol. I) and neural networks surgery (Vol. II) which uses neuro-engineering to improve impaired neural function.Vol. 2 describes the techniques and procedures applied by direct a) contact with the central nervous system or cranial nerves, in order to modulate the function of neural networks as in the case of motor cortext stimulation for pain or vagus nerve stimulation for epilepsy, or b) in deeply located structures inside the nervous system, in order to alter the function on specific networks as in the case of deep brain stimulation for Parkinson's disease.
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Our Land, Our Oil!: Natural Resources, Local Nationalism, and Violent Secession By Stefano Casertano (auth.)
2013 | 290 Pages | ISBN: 3531194429 | PDF | 3 MB
Stefano Casertano explores the connections between the presence of energy natural resources and the development of "local nationalism" in the producing regions. In particular, he applies a specific focus on those cases where such nationalism leads to secession attempts. The research is based on eight case studies in Bolivia, Sudan, Malaysia, Indonesia, China, Iran, Angola, and Nigeria.
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Roderick Hunt, "Oxford Phonics Spelling Dictionary"
English | ISBN: 019273413X | 2001 | pages | PDF | 17 MB
The brand new Oxford Phonics Spelling Dictionary is an easy home and school reference tool. It supports the teaching of reading and spelling through synthetic phonics. Supported by the Floppy's Phonics Sounds and Letters Programme, it follows the Alphabetic Code Chart showing the sounds and alternative spellings that children will need to learn to become proficient readers and spellers. The words are ordered by initial sound and there are subsections to show how the same sounds appear in the middle or at the end of a word. The long vowel sounds and their alternative spellings appear in a separate section within the dictionary. This unique dictionary makes it easy to explain how 'sun' and 'Cinderella' both start with the 's' sound and how 'dance' has the same 's' sound at the end, while 'egg' and 'eat' start with the same letter but different sounds. With colourful illustrations by Alex Brychta and the familiar Oxford Reading Tree characters, this is a fun way to prepare for the phonics screening check. There is additional phonics support material and audio on the Oxford Owl website,
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Christophe Jaffrelot, "Pakistan at the Crossroads: Domestic Dynamics and External Pressures "
English | ISBN: 0231173067 | 2016 | 360 pages | EPUB | 1455 KB
In Pakistan at the Crossroads, top international scholars assess Pakistan's politics and economics and the challenges faced by its civil and military leaders domestically and diplomatically. Contributors examine the state's handling of internal threats, tensions between civilians and the military, strategies of political parties, police and law enforcement reform, trends in judicial activism, the rise of border conflicts, economic challenges, financial entanglements with foreign powers, and diplomatic relations with India, China, Iran, Saudi Arabia, Afghanistan, and the United States.
In addition to ethnic strife in Baluchistan and Karachi, terrorist violence in Pakistan in response to the American-led military intervention in Afghanistan and in the Federally Administered Tribal Areas by means of drones, as well as to Pakistani army operations in the Pashtun area, has reached an unprecedented level. There is a growing consensus among state leaders that the nation's main security threats may come not from India but from its spiraling internal conflicts, though this realization may not sufficiently dissuade the Pakistani army from targeting the country's largest neighbor. This volume is therefore critical to grasping the sophisticated interplay of internal and external forces complicating the country's recent trajectory.
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Paper Flowers: 15 Stylish Projects To Make Your Own by Sine Finne Frandsen, Sara Finne Frandsen
English | May 21, 2024 | ISBN: 1837831696 | 208 pages | MOBI | 50 Mb
Learn to make 15 beautiful crepe paper flowers and discover how to style them in your space.
This charmingly illustrated book includes 15 flower projects of varying degrees of difficulty, ranging from a mini anemone and striped orchid to an impressive flamingo flower and a meadow buttercup. Master the art of making and adapting the flowers through the step-by-step instructions and create a stunning array of blooms to display in your home.
In this book, Sine and Sara Finne Fransen ofAlmeja Space guide you through a crash course in color theory and styling tips for every occasion. Discover how colors evoke different moods and create unique color combinations for your flowers.
Featuring chapters on materials, techniques and how to care for your blooms, Paper Flowers covers everything you need to create flowers that last (almost) forever.
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Party-Voter Linkage in Africa: Ghana and Senegal in Comparative Perspective By Anja Osei (auth.)
2012 | 307 Pages | ISBN: 3531186124 | PDF | 2 MB
Parties in Africa are often described as organisationally and programmatically weak. On the other hand, they mobilise substantial numbers of voters at election time. This contradiction provokes an interesting question: How do political parties in Africa relate to the society? How do they mobilise their voters and sympathisers, and which strategies do they employ?Anja Osei analyses how parties in Ghana and Senegal adapt to their local context by employing locally embedded strategies.
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Patho-Epigenetics of Disease By Walter Doerfler MD (auth.), Janos Minarovits, Hans Helmut Niller (eds.)
2012 | 466 Pages | ISBN: 1461433444 | PDF | 5 MB
In multicellular organisms the establishment, maintenance, and programmed alterations of cell-type specific gene expression patterns are regulated by epigenetic mechanisms. Thus, epigenetic alterations (DNA methylation, DNA associated Polycomb-Trithorax protein complexes, histone modifications) ensure the unique transcriptional activity and phenotypic diversity of diploid cells that carry identical or nearly identical DNA sequences.Because DNA methyltransferase I (DNMT1) associates with replication foci during S phase and prefers hemimethylated DNA as a substrate, DNMT1 ensures the clonal propagation of cytosine methylation patterns (maintenance methylation). Thus, DNA methylation may provide a memory function by helping progeny cells to "remember" their proper cellular identity. An alternative system of epigenetic memory, the Polycomb and Trithorax groups of protein complexes, that may operate both independently from and in concert with DNA methylation, ensures the heritable regulation of gene expression via modification of histone tails. The complex interplay of epigenetic regulatory mechanisms permits both the dynamic modulation of gene expression and the faithful transmission of gene expression patterns to each progeny cell upon division. These carefully orchestrated processes can go wrong, however, resulting in epigenetic reprogramming of the cells that may manifest in pathological changes, as it was first realized during the studies of epigenetic alterations in malignant tumors. By now it became a well established fact that not only genetic changes, but also the disruption of epigenetic regulation can result in carcinogenesis and tumor progression. Scientists working in other fields soon followed the pioneering work of cancer researchers, and revealed that epigenetic dysregulation forms the basis of a wide spectrum of human diseases.
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Pathology of the Pancreas: A Practical Approach by Fiona Campbell
English | EPUB | 2021 | 438 Pages | ISBN : 3030498476 | 843.9 MB
This updated volume provides a practical guide to pancreatic pathology that covers recent changes in concepts and classifications. Potential pitfalls and mimics in pancreatic pathology are highlighted and illustrated, and guidance is provided regarding how to recognise and avoid them. There is a new chapter on transplant pathology, and more than 200 new macroscopic and microscopic images have been added.
Pathology of the Pancreas: A Practical Approach aims to enable readers to recognise the various pathological entities and provide the key information in their pathology reports, which is necessary for the individual patient's further management. The book provides the diagnostic pathologist with a comprehensive, well-illustrated, and extensively cross-referenced approach to pancreatic pathology.
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Myŏngik Ch'oe, "Patterns of the Heart and Other Stories "
English | ISBN: 0231202709 | 2024 | 304 pages | PDF | 2 MB
Korean writer Ch'oe Myŏngik was a lifelong resident of Pyongyang, a city his short stories masterfully evoke in exquisite modernist prose. His career spanned decades of tumult, from his debut in the 1930s while Korea was under Japanese colonial rule through the Asia-Pacific and Korean Wars and the early years of the Democratic People's Republic. As Pyongyang transformed from Korea's second city, peripheral to the Seoul-centered literary scene, into a socialist capital in the late 1940s, Ch'oe briefly ascended to the center of North Korean culture. Despite the vitality and originality of Ch'oe's writing, Cold War politics and censorship, including South Korea's anticommunist laws, consigned his work to obscurity.
Patterns of the Heart and Other Stories presents a selection of Ch'oe's short fiction in translation, including later works from hard-to-find North Korean publications. These cinematic, keenly observed tales explore Pyongyang in meticulous detail, depicting the city's transformations and the conflicts between old and new. They pay close attention to the lives of the disaffected and the marginalized: a drifter confronts a former revolutionary dying of opium addiction; a sex worker is trafficked across the border aboard a train, amid the indifference of her fellow passengers. Later stories provide a striking glimpse of the Korean War-the occupation of Pyongyang, U.S. fighter jets bombing civilian refugees, guerrilla heroics-from a North Korean perspective. Hidden treasures of world literature, these stories offer new perspectives on Korea's turbulent twentieth century, across political divides still in place today.
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Pediatric Endocrinology: A Practical Clinical Guide, Second Edition By Christopher J. Romero M.D., Andrew N. Dauber M.D., Laurie E. Cohen M.D. (auth.), Sally Radovick, Margaret H. MacGillivray (eds.)
2013 | 624 Pages | ISBN: 1607613948 | PDF | 12 MB
A state-of-the-art and concise guide to the clinical management of pediatric endocrine disorders, the second edition of the highly regarded Pediatric Endocrinology: A Practical Clinical Guide covers the most common and challenging conditions seen by practicing endocrinologists and primary care physicians, including growth, hypothalamic, pituitary, adrenal, thyroid, calcium and bone, and reproductive disorders, as well as metabolic syndromes. This expanded second edition includes new topics being seen more commonly in pediatric endocrinology practices related to obesity and type 2 diabetes mellitus and lipid disorders. Each chapter contains an introductory discussion of the problem, a review of the clinical features that characterize it, the criteria needed to establish a diagnosis, and a comprehensive therapy section delineating the risks and benefits of the best therapeutic options available. Invaluable tables summarize the critical factors in etiology, clinical presentation, diagnosis, and therapeutic dosages. Pediatric Endocrinology: A Practical Clinical Guide, Second Edition, is a comprehensive resource for all clinicians concerned with the myriad endocrinologic disorders seen in children and adolescents.
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